A client taking digoxin complains of nausea and generalized weakness. What should the nurse do first?

Checking the client's vital signs is the most appropriate first step in this scenario because the symptoms of nausea and generalized weakness can indicate several potential issues, including digoxin toxicity or instability in the client’s overall health status. Vital signs can provide immediate, critical information about the client's current condition, such as heart rate and rhythm, which are particularly important in the context of digoxin use, as it is known to affect cardiac function.

In cases of suspected digoxin toxicity, changes in heart rate may be observed, such as bradycardia, which can be life-threatening. Assessing vital signs can guide further interventions and determine the urgency of notifying the healthcare provider or administering any medications. This initial assessment is essential before proceeding with any other actions, such as administering anti-nausea medication or digoxin. It ensures a comprehensive understanding of the client's condition, allowing for more informed and effective decision-making.